Description

[(1-Methyl-1,4-bipiperidin-4-yl)methyl]amine dihydrochloride CAS NO 1269050-34-1 is a high-purity, specialized organic salt primarily utilized as a critical building block in advanced pharmaceutical research and development. This compound serves as a key intermediate for synthesizing novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and other therapeutic areas. It is essential for medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries who require reliable, high-quality intermediates for drug discovery and scale-up.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel drug candidates, especially for neurological and psychiatric applications.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to create new chemical entities.
• Process Chemistry & Scale-Up: Serves as a critical building block for the pilot-scale and commercial-scale synthesis of target Active Pharmaceutical Ingredients (APIs).
• Ligand Synthesis: Can be utilized in the preparation of specialized ligands for catalytic or biochemical applications.
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying biological pathways and target validation.

Basic Information

Product Name	[(1-Methyl-1,4-bipiperidin-4-yl)methyl]amine dihydrochloride
CAS No.	1269050-34-1
Molecular Formula	C12H25N3 • 2HCl
Molecular Weight	284.27 g/mol (Free base: 211.35 g/mol)
Synonyms	1-[(1-Methyl-4-piperidinyl)methyl]-4-piperidinamine dihydrochloride; 4-[(Aminomethyl)-1-methyl-4-piperidyl]piperidine dihydrochloride; (1-Methyl-1,4-bipiperidin-4-yl)methanamine dihydrochloride; 1-Methyl-4-(aminomethyl)-4-piperidinopiperidine dihydrochloride; 4-(Aminomethyl)-1-methyl-4-piperidinopiperidine dihydrochloride; Amine derivative of 1-methyl-1,4-bipiperidine dihydrochloride
EINECS	Contact for details

Quality Control

Our [(1-Methyl-1,4-bipiperidin-4-yl)methyl]amine dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.