Description

3-(Aminomethyl)-1,2-Dihydroquinolin-2-One Hydrochloride is a high-purity, pharmaceutically relevant organic compound, primarily utilized as a key synthetic intermediate or building block in medicinal chemistry. Its value lies in enabling the efficient construction of complex nitrogen-containing heterocycles, which are core scaffolds in many active pharmaceutical ingredients. This product is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new therapeutic agents or advanced materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel quinoline-based drug candidates, including potential kinase inhibitors and central nervous system (CNS) agents.
• Medicinal Chemistry Research: Used in high-throughput screening libraries and structure-activity relationship (SAR) studies to explore new bioactive molecules.
• Agrochemical Synthesis: Serves as a precursor in the development of new herbicides, fungicides, or insecticides with quinoline motifs.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and advanced materials.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	3-(Aminomethyl)-1,2-Dihydroquinolin-2-One Hydrochloride
CAS No.	1266690-76-9
Molecular Formula	C10H11N2O·HCl
Molecular Weight	210.67 g/mol
Synonyms	2-Oxo-1,2-dihydroquinoline-3-methanamine hydrochloride; 3-(Aminomethyl)-2-hydroxyquinoline hydrochloride; 1,2-Dihydro-2-oxoquinoline-3-methanamine hydrochloride; 3-(Aminomethyl)quinolin-2(1H)-one hydrochloride; Quinolin-2(1H)-one, 3-(aminomethyl)-, hydrochloride; 3-Aminomethyl-1,2-dihydro-2-oxoquinoline HCl; 3-Carbamoylmethylquinolin-2-one hydrochloride (common misnomer); 1266690-76-9
EINECS	Contact for details

Quality Control

Our 3-(Aminomethyl)-1,2-Dihydroquinolin-2-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), residual solvents, and other critical parameters is provided with every shipment to guarantee reliable and reproducible performance in your synthetic workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.