Description

1-tert-Butyl-1H-Pyrrole-3-Carboxylic Acid is a specialized pyrrole derivative carboxylic acid, serving as a high-value building block in advanced organic synthesis. Its unique structure, featuring a sterically hindered tert-butyl group adjacent to the pyrrole nitrogen, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of drug candidates, especially those targeting central nervous system (CNS) disorders or requiring specific steric and electronic profiles.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the pyrrole scaffold imparts specific biological activity.
• Material Science: Serves as a precursor for functional polymers, organic semiconductors, and advanced ligands for metal-organic frameworks (MOFs) or catalysts.
• Chemical Synthesis: Acts as a versatile synthon for creating more complex heterocyclic compounds through reactions at the carboxylic acid group or the pyrrole ring.
• Academic & R&D: Employed in university and corporate research laboratories for methodological studies and exploring new chemical spaces.

Basic Information

Product Name	1-tert-Butyl-1H-Pyrrole-3-Carboxylic Acid
CAS No.	1266364-46-8
Molecular Formula	C9H13NO2
Molecular Weight	167.21 g/mol
Synonyms	1-(1,1-Dimethylethyl)-1H-pyrrole-3-carboxylic acid; 1-tert-Butylpyrrole-3-carboxylic acid; 3-Carboxy-1-tert-butylpyrrole; 1-tert-Butyl-1H-pyrrole-3-carboxylate (acid); 1-(tert-Butyl)-1H-pyrrole-3-carboxylic acid; Pyrrole-3-carboxylic acid, 1-(1,1-dimethylethyl)-; 1266364-46-8
EINECS	Contact for details

Quality Control

Our 1-tert-Butyl-1H-Pyrrole-3-Carboxylic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) detailing all specifications is available with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its nature as a strong acid/organic solvent, keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.