Description

3-Amino-6-Fluoroquinoline Dihydrochloride is a high-purity, advanced pharmaceutical intermediate and research chemical. This compound is valued for its role as a critical building block in the synthesis of complex molecules, particularly in medicinal chemistry. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, including potential antibiotics and anticancer drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinolone and fluoroquinolone-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug candidates.
• Antibiotic Development: Serves as a core scaffold for developing next-generation antibacterial agents targeting DNA gyrase and topoisomerase IV.
• Oncology Research: Investigated as a building block for potential anticancer compounds due to the quinoline moiety's biological activity.
• Chemical Synthesis: Utilized in organic synthesis for introducing the amino-fluoroquinoline structure into more complex molecules.
• Biochemical Research: Employed as a standard or reagent in biochemical assays and studies involving enzyme inhibition.

Basic Information

Product Name	3-Amino-6-Fluoroquinoline Dihydrochloride
CAS No.	1266226-23-6
Molecular Formula	C9H8FN2 • 2HCl
Molecular Weight	239.10 g/mol (Free base: 162.17 g/mol)
Synonyms	6-Fluoro-3-quinolinamine dihydrochloride; 3-Amino-6-fluoroquinoline hydrochloride (1:2); 3-Amino-6-fluoroquinoline HCl; 6-Fluoroquinolin-3-amine dihydrochloride; 3-Amino-6-fluoroquinoline 2HCl; 1266226-23-6; 3-Amino-6-fluoroquinoline dihydrochloride salt
EINECS	Contact for details

Quality Control

Our 3-Amino-6-Fluoroquinoline Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.