Description

Spiro[4.5]Decan-8-Ol CAS NO 1266120-78-8 is a specialized spirocyclic alcohol compound characterized by its unique bridged bicyclic structure. This molecular architecture makes it a valuable and versatile chiral building block and intermediate in advanced organic synthesis. It is particularly sought after by research and development teams in the pharmaceutical and fine chemical industries. The compound's defined stereochemistry and functional group are critical for constructing complex molecules with specific biological activity.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic agents.
• Asymmetric Synthesis: Used as a precursor or auxiliary in catalytic asymmetric reactions to introduce stereogenic centers into target molecules.
• Fragrance and Flavor Chemistry: Acts as a starting material for the synthesis of novel musk-like or woody odorants due to its complex spirocyclic backbone.
• Material Science Research: Investigated as a monomer or functional additive for creating polymers with specific thermal or mechanical properties.
• Agrochemical Synthesis: Employed in the development of novel pesticides and herbicides where its rigid structure can enhance biological activity and stability.
• Academic and R&D Laboratories: Utilized in methodological studies and the discovery of new synthetic pathways in organic chemistry.

Basic Information

Product Name	Spiro[4.5]Decan-8-Ol
CAS No.	1266120-78-8
Molecular Formula	C₁₀H₁₈O
Molecular Weight	154.25 g/mol
Synonyms	Spiro[4.5]decan-8-ol; 8-Hydroxyspiro[4.5]decane; 1-Oxaspiro[2.6]nonan-4-ol (related bicyclic representation); Spirodecanol; Bicyclo[3.3.1]nonan-9-ol, 2-oxa- (alternative bridgehead system); 8-Spirodecanol; Spirocyclic decanol
EINECS	Contact for details

Quality Control

We maintain a strict quality management system to ensure batch-to-batch consistency and high purity for our advanced intermediates. Production is supported by modern analytical techniques including GC, HPLC, and NMR. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment. Specifications can be developed to meet the specific requirements of cGMP or other regulatory frameworks for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage under an inert atmosphere (nitrogen or argon), please contact us.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥97.0% (Standard Grade)
Melting Point	Contact for details
Specific Rotation	Contact for details
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	<10 ppm
Water Content (KF)	<0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.