Description

(4S)-2-(2-Hydroxy-3-Methoxyphenyl)-1,3-Thiazolidine-4-Carboxylic Acid is a chiral, non-proteinogenic amino acid derivative featuring a thiazolidine ring, a structure of significant interest in advanced organic synthesis and pharmaceutical research. This compound matters as a sophisticated building block or key intermediate for the development of novel bioactive molecules, particularly in medicinal chemistry programs. It is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of peptidomimetics, enzyme inhibitors, and other complex therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and metabolic disorders.
• Peptidomimetic Chemistry: Used as a constrained amino acid analog to design and synthesize peptide-like molecules with enhanced metabolic stability and bioavailability.
• Chemical Biology Probe Development: Acts as a scaffold for creating tool compounds to study enzyme function and protein-protein interactions.
• Asymmetric Synthesis: Employed as a starting material or auxiliary in stereoselective synthesis to introduce chiral centers into complex molecular architectures.
• Ligand and Catalyst Research: Investigated for use in the development of novel chiral ligands or organocatalysts for asymmetric transformations.

Basic Information

Product Name	(4S)-2-(2-Hydroxy-3-Methoxyphenyl)-1,3-Thiazolidine-4-Carboxylic Acid
CAS No.	1265908-02-8
Molecular Formula	C11H13NO4S
Molecular Weight	255.29 g/mol
Synonyms	(4S)-2-(2-Hydroxy-3-methoxyphenyl)-1,3-thiazolidine-4-carboxylic acid; (S)-2-(2-Hydroxy-3-methoxyphenyl)thiazolidine-4-carboxylic acid; L-Thiazolidine-4-carboxylic acid, 2-(2-hydroxy-3-methoxyphenyl)-, (4S)-; 1,3-Thiazolidine-4-carboxylic acid, 2-(2-hydroxy-3-methoxyphenyl)-, (4S)-; 1265908-02-8; (S)-2-(2-Hydroxy-3-methoxyphenyl)-1,3-thiazolidin-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including HPLC, NMR, and chiral analysis to guarantee high chemical and enantiomeric purity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request. Our quality management system supports production under cGMP guidelines for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider inert atmosphere conditions to ensure stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.