Description

6-(tert-Butyl)Pyridine-2-Boronic Acid is a specialized organoboron compound that serves as a versatile building block in modern synthetic chemistry. Its value lies in its role as a key coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality reagents for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing functionalized pyridine scaffolds.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that incorporate the tert-butylpyridine moiety.
• Material Science: Employed in the development of organic electronic materials, such as ligands for catalysts and components for organic light-emitting diodes (OLEDs).
• Chemical Research: A valuable reagent in academic and industrial R&D for constructing complex molecular architectures via palladium-catalyzed cross-coupling reactions.
• Ligand Synthesis: Serves as a starting material for the preparation of sophisticated ligands used in homogeneous catalysis.
• Library Synthesis: Facilitates the rapid generation of diverse compound libraries for high-throughput screening in drug discovery programs.

Basic Information

Product Name	6-(tert-Butyl)Pyridine-2-Boronic Acid
CAS No.	1265478-40-7
Molecular Formula	C9H14BNO2
Molecular Weight	179.03 g/mol
Synonyms	2-(6-(tert-Butyl)pyridin-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 6-tert-Butylpyridine-2-boronic acid; 6-tert-Butyl-2-pyridineboronic acid; 2-Borono-6-tert-butylpyridine; 6-(1,1-Dimethylethyl)-2-pyridineboronic acid; Pinacol 6-(tert-butyl)pyridine-2-boronate; 6-tert-Butyl-2-pyridinylboronic acid
EINECS	Contact for details

Quality Control

Our 6-(tert-Butyl)Pyridine-2-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive coupling reactions. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring traceability and consistency for our global customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.