Description

4-Chloro-3-Methylbenzylamine Hydrochloride is a high-purity, functionalized benzylamine derivative supplied as a stable hydrochloride salt. This compound serves as a critical pharmaceutical intermediate and versatile organic building block for the synthesis of more complex molecules. It is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce a chloromethylbenzylamine moiety into target structures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the chloromethylaniline scaffold.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands for asymmetric catalysis or as a precursor for metal-organic frameworks (MOFs).
• Organic Synthesis Research: Versatile starting material for amide formation, reductive amination, and nucleophilic substitution reactions in academic and industrial R&D laboratories.
• Dye and Pigment Chemistry: Intermediate in the production of specialized dyes and pigments, where the amine group facilitates coupling reactions.
• Polymer Modification: Functional monomer or cross-linking agent for creating specialty polymers with tailored properties.

Basic Information

Product Name	4-Chloro-3-Methylbenzylamine Hydrochloride
CAS No.	1264198-68-6
Molecular Formula	C8H10ClN • HCl
Molecular Weight	192.52 g/mol (Free base: 155.63 g/mol)
Synonyms	(4-Chloro-3-methylphenyl)methanamine hydrochloride; 1-(4-Chloro-3-methylphenyl)methanamine hydrochloride; 4-Chloro-3-methylbenzenemethanamine hydrochloride; α-Amino-4-chloro-3-methyltoluene hydrochloride; 3-Methyl-4-chlorobenzylamine HCl; 4-Chloro-m-tolylmethylamine hydrochloride; 4-Chloro-3-methylbenzylamine HCl
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Methylbenzylamine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, impurity profiles, and physical characteristics. Our quality commitment supports compliance with cGMP and ICH guidelines for use as a pharmaceutical intermediate.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere (nitrogen or argon) to prevent moisture absorption and degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.