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9-Amino-(9-Deoxy)Epi-Cinchonidine Trihydrochloride CAS NO 1263486-03-8


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CAS No.:1263486-03-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

9-Amino-(9-Deoxy)Epi-Cinchonidine Trihydrochloride is a high-purity, chiral organic salt derived from the cinchona alkaloid family. This compound serves as a critical chiral ligand, catalyst, or resolving agent in asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control.

Application

  • Asymmetric Catalysis: As a chiral ligand or organocatalyst for enantioselective carbon-carbon and carbon-heteroatom bond-forming reactions.
  • Pharmaceutical Intermediate: In the synthesis of active pharmaceutical ingredients (APIs) requiring high enantiomeric purity.
  • Chiral Resolution: As a resolving agent for the separation of racemic mixtures of carboxylic acids, alcohols, and other functional groups.
  • Method Development: For developing and optimizing new asymmetric synthetic methodologies in academic and industrial R&D laboratories.
  • Agrochemical Synthesis: In the production of chiral pesticides and herbicides where specific stereoisomers exhibit desired biological activity.
  • Reference Standard: Used as an analytical standard for quality control and method validation in chiral analysis (e.g., HPLC, SFC).

Basic Information

Product Name 9-Amino-(9-Deoxy)Epi-Cinchonidine Trihydrochloride
CAS No. 1263486-03-8
Molecular Formula C19H27Cl3N2O
Molecular Weight 405.79 g/mol
Synonyms (8α,9R)-9-Amino-10,11-dihydro-6'-methoxycinchonan-9-ol trihydrochloride; 9-Amino-9-deoxyepi-cinchonidine trihydrochloride; 9-ADEC trihydrochloride; 9-Aminoepicinchonidine trihydrochloride; (9R)-9-Amino-9-deoxyepi-cinchonidine hydrochloride (1:3); Cinchonidine, 9-amino-9-deoxy-, trihydrochloride, (8α,9R)-; 9-Amino-DEC trihydrochloride
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Quality Control

Our 9-Amino-(9-Deoxy)Epi-Cinchonidine Trihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing purity, assay, and identity is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Chiral Purity (HPLC) ≥ 99.0% ee
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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