Description

Pyrrolidin-2-Yl-Acetic Acid Methyl Ester Hydrochloride is a high-purity organic salt and a key chiral intermediate in advanced pharmaceutical synthesis. Its pyrrolidine core structure makes it a valuable building block for constructing complex molecules with specific biological activity. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where specific stereochemistry is required for efficacy.
• Chemical Research & Development: Serves as a versatile starting material in academic and industrial R&D for exploring new chemical entities and reaction pathways.
• Peptidomimetics: Employed in the design and synthesis of peptide analogs and protease inhibitors due to its proline-like structure.
• Asymmetric Catalysis: Can be used as a precursor for chiral ligands or catalysts in enantioselective synthesis.

Basic Information

Product Name	Pyrrolidin-2-Yl-Acetic Acid Methyl Ester Hydrochloride
CAS No.	1263378-78-4
Molecular Formula	C7H14ClNO2
Molecular Weight	179.65 g/mol
Synonyms	Methyl 2-(pyrrolidin-2-yl)acetate hydrochloride; (S)-(-)-2-(Methoxycarbonylmethyl)pyrrolidine hydrochloride; L-Proline methyl ester hydrochloride (derivative); 2-Pyrrolidineacetic acid, methyl ester, hydrochloride; Methyl (2S)-2-(pyrrolidin-2-yl)acetate hydrochloride
EINECS	Contact for details

Quality Control

Our Pyrrolidin-2-Yl-Acetic Acid Methyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, which includes data from chiral HPLC, NMR, and other relevant methods to confirm compliance with customer specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.