Description

4-(4-Bromo-Pyrazol-1-Yl)-Piperidine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1263378-44-4. This compound is a critical building block in modern medicinal chemistry, valued for its piperidine-pyrazole hybrid structure which is integral to modulating biological activity. It is primarily sought after by research and development teams in the pharmaceutical and biotechnology sectors for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• CNS Drug Development: Serves as a core scaffold for compounds intended to interact with neurological receptors and enzymes.
• Oncology Research: Employed in the development of kinase inhibitors and other targeted cancer therapies.
• Chemical Biology: Utilized as a molecular probe to study biological pathways and protein function.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	4-(4-Bromo-Pyrazol-1-Yl)-Piperidine Hydrochloride
CAS No.	1263378-44-4
Molecular Formula	C8H13BrClN3
Molecular Weight	266.56 g/mol
Synonyms	4-(4-Bromo-1H-pyrazol-1-yl)piperidine hydrochloride; 1-(4-Bromo-1H-pyrazol-1-yl)-4-piperidine hydrochloride; 4-(4-Bromopyrazol-1-yl)piperidine HCl; Piperidine, 4-(4-bromo-1H-pyrazol-1-yl)-, hydrochloride; 1263378-44-4; 4-(4-Bromo-1-pyrazolyl)piperidine hydrochloride
EINECS	Contact for details

Quality Control

Our 4-(4-Bromo-Pyrazol-1-Yl)-Piperidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring material integrity for sensitive research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.