Description

(2-Trifluoromethyl-Benzyl)-Hydrazine Hydrochloride is a specialized organic building block featuring a benzyl hydrazine core substituted with a trifluoromethyl group. This compound is valued for its role as a key intermediate in the synthesis of more complex molecules, particularly in pharmaceutical and agrochemical research. Its unique structure, combining a hydrazine moiety with a fluorine-containing aromatic ring, makes it essential for medicinal chemists and process development scientists. Target industries include pharmaceutical R&D, agrochemical manufacturing, and advanced material science.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Heterocyclic Chemistry: Employed in the construction of nitrogen-containing heterocycles like pyrazoles, triazoles, and indazoles, which are common scaffolds in drug discovery.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and protein interactions.
• Material Science Research: Investigated as a monomer or cross-linking agent in the development of advanced polymers with specific thermal or chemical resistance properties.

Basic Information

Product Name	(2-Trifluoromethyl-Benzyl)-Hydrazine Hydrochloride
CAS No.	1263378-37-5
Molecular Formula	C8H9ClF3N2
Molecular Weight	224.62 g/mol
Synonyms	1-[(2-Trifluoromethyl)phenyl]methylhydrazine hydrochloride; 2-(Trifluoromethyl)benzylhydrazine hydrochloride; α-(Trifluoromethyl)benzylhydrazine hydrochloride; (2-(Trifluoromethyl)phenyl)methanamine, N-amino-, hydrochloride; 1-(2-Trifluoromethylbenzyl)hydrazine hydrochloride; Hydrazine, [(2-(trifluoromethyl)phenyl)methyl]-, hydrochloride; Benzenemethanamine, 2-(trifluoromethyl)-, hydrazone, hydrochloride
EINECS	Contact for details

Quality Control

Our (2-Trifluoromethyl-Benzyl)-Hydrazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.