Description

5-Bromo-2-Iodo-3-Methylbenzoic Acid is a high-purity halogenated benzoic acid derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique substitution pattern makes it a valuable building block for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. This compound is essential for medicinal chemists and process development scientists seeking to introduce specific halogen functionalities into target molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides and fungicides, where the bromine and iodine atoms can be leveraged for structure-activity relationship (SAR) studies.
• Ligand Synthesis: Precursor for creating specialized ligands in catalysis and materials science, including those for cross-coupling reactions like Suzuki-Miyaura and Buchwald-Hartwig amination.
• Material Science Monomer: Serves as a functional monomer for synthesizing advanced polymers with specific electronic or photophysical properties.
• Chemical Biology Probe Development: Utilized in the design of molecular probes and tags for studying biological processes due to its potential for further functionalization.
• Academic & Contract Research: A vital reagent for universities and CROs (Contract Research Organizations) engaged in methodological development and novel heterocycle synthesis.

Basic Information

Product Name	5-Bromo-2-Iodo-3-Methylbenzoic Acid
CAS No.	1263376-42-6
Molecular Formula	C8H6BrIO2
Molecular Weight	340.94 g/mol
Synonyms	3-Methyl-5-bromo-2-iodobenzoic acid; 2-Iodo-5-bromo-3-methylbenzoic acid; Benzoic acid, 5-bromo-2-iodo-3-methyl-; 5-Bromo-2-iodo-m-toluic acid; 1263376-42-6; 5-Br-2-I-3-Me-BA
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Iodo-3-Methylbenzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and elemental analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production standards. Specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.