Description

Ethyl 3-Amino-2,2-Difluoropropanoate Hydrochloride is a high-purity fluorinated organic building block, essential for the synthesis of complex molecules in advanced research and development. Its value lies in the unique reactivity of the amino and difluoroacetate ester groups, which are critical for introducing specific structural motifs into target compounds. This material is primarily needed by pharmaceutical, agrochemical, and specialty chemical manufacturers for applications in medicinal chemistry, process development, and the creation of novel fluorinated materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated amino acid analogs or bioactive molecules with enhanced metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where fluorine atoms improve efficacy and environmental profile.
• Peptidomimetics & Bioactive Molecule Design: Serves as a versatile building block for constructing peptide mimics and other biologically active compounds in drug discovery programs.
• Fluorinated Material Research: Employed in academic and industrial R&D for synthesizing novel fluorinated polymers, liquid crystals, or specialty chemicals with unique properties.
• Process Chemistry & Scale-up: Provides a reliable starting material for optimizing synthetic routes and scaling up production of target molecules in pilot plants and manufacturing.

Basic Information

Product Name	Ethyl 3-Amino-2,2-Difluoropropanoate Hydrochloride
CAS No.	1263284-04-3
Molecular Formula	C5H10F2NO2·HCl
Molecular Weight	197.60 g/mol (Free base: 155.14 g/mol)
Synonyms	2,2-Difluoro-3-aminopropanoic Acid Ethyl Ester Hydrochloride; Ethyl 3-Amino-2,2-difluoropropionate Hydrochloride; 3-Amino-2,2-difluoropropionic Acid Ethyl Ester Hydrochloride; Ethyl 2,2-Difluoro-3-aminopropanoate HCl; 1263284-04-3; Amino Difluoropropanoate Ester HCl Salt
EINECS	Contact for details

Quality Control

Our Ethyl 3-Amino-2,2-Difluoropropanoate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.