Description

8-Bromo-4-Chloro-2,6-Dimethylquinazoline is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its value lies in its unique halogenated and dimethylated quinazoline scaffold, which provides versatile reactivity for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides due to its bioactive quinazoline core.
• Material Science: Acts as a building block for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways.
• Custom Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects requiring functionalized quinazoline derivatives.
• Academic Research: A valuable reagent for methodological studies in organic chemistry, including cross-coupling and halogen-metal exchange reactions.

Basic Information

Product Name	8-Bromo-4-Chloro-2,6-Dimethylquinazoline
CAS No.	1263283-41-5
Molecular Formula	C10H8BrClN2
Molecular Weight	287.54 g/mol
Synonyms	8-Bromo-4-chloro-2,6-dimethylquinazoline; 2,6-Dimethyl-8-bromo-4-chloroquinazoline; Quinazoline, 8-bromo-4-chloro-2,6-dimethyl-; 4-Chloro-8-bromo-2,6-dimethylquinazoline; 8-Bromo-4-chloro-2,6-dimethyl-quinazoline
EINECS	Contact for details

Quality Control

Our 8-Bromo-4-Chloro-2,6-Dimethylquinazoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.