Description

6-Bromo-8-(4-Methylpiperazin-1-Yl)-1,2,3,4-Tetrahydro-1,5-Naphthyridine is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure. This compound is of significant commercial interest for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of targeted therapies, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel small-molecule drug candidates.
• Kinase Inhibitor Synthesis: Serves as a core scaffold for the construction of potential kinase inhibitors, targeting various cancer pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations for custom synthesis and scale-up projects.
• Biochemical Tool Compound: May be utilized in vitro as a probe to study specific biological mechanisms and target validation.

Basic Information

Product Name	6-Bromo-8-(4-Methylpiperazin-1-Yl)-1,2,3,4-Tetrahydro-1,5-Naphthyridine
CAS No.	1263212-76-5
Molecular Formula	C13H18BrN5
Molecular Weight	324.22 g/mol
Synonyms	6-Bromo-8-(4-methyl-1-piperazinyl)-1,2,3,4-tetrahydro-1,5-naphthyridine; 1,2,3,4-Tetrahydro-6-bromo-8-(4-methyl-1-piperazinyl)-1,5-naphthyridine; 6-Bromo-8-(4-methylpiperazin-1-yl)-1,2,3,4-tetrahydro-1,5-naphthyridine; 1263212-76-5; 8-(4-Methylpiperazin-1-yl)-6-bromo-1,2,3,4-tetrahydro-1,5-naphthyridine
EINECS	Contact for details

Quality Control

Our 6-Bromo-8-(4-Methylpiperazin-1-Yl)-1,2,3,4-Tetrahydro-1,5-Naphthyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound is light-sensitive (store away from light) and hygroscopic (moisture-sensitive). For long-term storage, consider desiccation and an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.