Description

2-Thia-6-Azaspiro[3.3]Heptane 2,2-Dioxide is a high-value, spirocyclic sulfonamide building block of significant interest in modern pharmaceutical and agrochemical research. Its unique, rigid three-dimensional structure makes it a privileged scaffold for designing novel bioactive molecules with enhanced properties. This compound is primarily sought after by R&D chemists and process development scientists in the life sciences sector for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and metabolic disease targets.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging its spirocyclic core for improved bioactivity.
• Chemical Biology Probe: Serves as a versatile scaffold for creating tool compounds and probes to study biological pathways and protein function.
• Material Science Precursor: Potential use in synthesizing specialty polymers and advanced materials with specific sulfonamide functionalities.
• Library Synthesis for Drug Discovery: Employed in high-throughput and parallel synthesis to generate diverse compound libraries for screening.
• Process Chemistry & Scale-Up: Used in route development and optimization for the commercial-scale production of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	2-Thia-6-Azaspiro[3.3]Heptane 2,2-Dioxide
CAS No.	1263182-09-7
Molecular Formula	C5H9NO2S
Molecular Weight	147.20 g/mol
Synonyms	2-Thia-6-azaspiro[3.3]heptane 2,2-dioxide; 1,4-Thiaza-6-azaspiro[3.3]heptane 1,1-dioxide; 6-Aza-2-thiaspiro[3.3]heptane 2,2-dioxide; Spiro[cyclopropane-1,3'-[1,4]thiazinane] 1',1'-dioxide; 2-Thia-6-azaspiro[3.3]heptane, 2,2-dioxide; Sulfonyl Spirocyclic Amine; 1-Oxa-4-thia-6-azaspiro[2.4]heptane 4,4-dioxide (related structure); Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our 2-Thia-6-Azaspiro[3.3]Heptane 2,2-Dioxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) with full analytical data are provided for every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.