Description

n-(1R,8S,9S)-Bicyclo[6.1.0]Non-4-Yn-9-Ylmethyloxycarbonyl-1,8-Diamino-3,6-Dioxaoctane is a specialized, high-purity chemical building block designed for advanced synthesis. This compound matters for its role as a key intermediate in click chemistry and bioconjugation, enabling precise and efficient molecular assembly. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for developing targeted therapeutics, diagnostics, and functional polymers.

Application

• Bioconjugation Reagent: For site-specific labeling of proteins, antibodies, and oligonucleotides in diagnostic and therapeutic development.
• Click Chemistry Intermediate: Enables copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for polymer and material science.
• Pharmaceutical Intermediate: Used in the synthesis of complex active pharmaceutical ingredients (APIs) and antibody-drug conjugates (ADCs).
• Proteomics Research: Acts as a functional linker for affinity probes and activity-based protein profiling (ABPP).
• Polymer Functionalization: Introduces reactive handles onto polymer backbones for creating smart materials and hydrogels.
• Chemical Biology Tool: Facilitates the study of biomolecular interactions and cellular processes through bioorthogonal chemistry.

Basic Information

Item	Information
Product Name	n-(1R,8S,9S)-Bicyclo[6.1.0]Non-4-Yn-9-Ylmethyloxycarbonyl-1,8-Diamino-3,6-Dioxaoctane
CAS No.	1263166-93-3
Molecular Formula	C19H28N2O5
Molecular Weight	364.44 g/mol
Synonyms	BCN-PEG3-amine; BCN-NH2; (1R,8S,9S)-Bicyclo[6.1.0]non-4-yn-9-ylmethyl (2,5,8,11-tetraoxatridecan-13-yl)carbamate; BCN-PEG3-NH2; BCN-amine-PEG3; BCN-PEG(3)-amine; BCN-PEG3-Amine; BCN-PEG3-NH2
EINECS	Contact for details

Quality Control

Our n-(1R,8S,9S)-Bicyclo[6.1.0]Non-4-Yn-9-Ylmethyloxycarbonyl-1,8-Diamino-3,6-Dioxaoctane is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting compliance with research and cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) in a cool, dry place. This product is hygroscopic (moisture-sensitive) and light-sensitive; allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.