Description

(R)-1-(5-Bromo-Pyridin-2-Yl)-Ethylamine Dihydrochloride CAS NO 1263094-16-1 is a high-purity chiral amine derivative, specifically the (R)-enantiomer, which serves as a critical building block in advanced organic synthesis. Its value lies in its role as a key intermediate for constructing complex molecules with defined stereochemistry, essential for developing active pharmaceutical ingredients (APIs) and other fine chemicals. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries focused on chiral drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the production of advanced, enantiomerically pure pesticides and herbicides where specific stereochemistry impacts biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to control reaction stereoselectivity.
• Chemical Biology Research: Employed in the synthesis of molecular probes and tool compounds for studying biological pathways and enzyme mechanisms.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring a defined (R)-configured ethylamine moiety attached to a bromopyridine scaffold.

Basic Information

Product Name	(R)-1-(5-Bromo-Pyridin-2-Yl)-Ethylamine Dihydrochloride
CAS No.	1263094-16-1
Molecular Formula	C7H10BrCl2N2
Molecular Weight	282.98 g/mol
Synonyms	(R)-1-(5-Bromopyridin-2-yl)ethan-1-amine dihydrochloride; (R)-1-(5-Bromo-2-pyridinyl)ethylamine dihydrochloride; (R)-α-Methyl-5-bromo-2-pyridinemethanamine dihydrochloride; (R)-5-Bromo-2-(1-aminoethyl)pyridine dihydrochloride; (R)-1-(5-Bromo-2-pyridyl)ethylamine hydrochloride (1:2); (R)-1-(5-Bromopyrid-2-yl)ethylammonium chloride
EINECS	Contact for details

Quality Control

Our (R)-1-(5-Bromo-Pyridin-2-Yl)-Ethylamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-purity research and development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically ≥97% by HPLC), chiral excess, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.