Description

Z-Dbu-Ome.Hcl (S) is a high-purity, chiral amino acid derivative widely utilized as a critical building block in advanced organic synthesis. Its primary value lies in enabling the precise construction of complex peptide and peptidomimetic structures, which are essential for pharmaceutical research and development. This compound is particularly vital for medicinal chemists and process development scientists working in the fields of drug discovery, proteomics, and the synthesis of active pharmaceutical ingredients (APIs).

Application

• Peptide Synthesis: A key protected amino acid building block for solid-phase and solution-phase peptide synthesis (SPPS).
• Pharmaceutical Intermediates: Used in the research and development of novel therapeutic peptides and peptidomimetics.
• Protease Inhibitor Development: Serves as a core structural component in the design of enzyme inhibitors.
• Bioconjugation: Employed in the chemical modification of proteins and other biomolecules for research and diagnostic applications.
• Chemical Biology Probes: Integral for synthesizing labeled peptides and activity-based probes used in mechanistic studies.
• Academic & Industrial R&D: A fundamental reagent for exploring new synthetic methodologies and bioactive compound libraries.

Basic Information

Product Name	Z-Dbu-Ome.Hcl (S)
CAS No.	1263047-39-7
Molecular Formula	C15H20N2O4 • HCl
Molecular Weight	328.79 g/mol (Free base: 292.33 g/mol)
Synonyms	Nα-Carbobenzyloxy-L-2,4-diaminobutyric acid methyl ester hydrochloride; Z-L-Dab-OMe • HCl; Cbz-L-Dab-OMe • HCl; (S)-Methyl 2-((((benzyloxy)carbonyl)amino)-4-aminobutanoate hydrochloride; (S)-Methyl 4-amino-2-((benzyloxycarbonyl)amino)butanoate hydrochloride; Nα-Cbz-L-2,4-diaminobutyric acid methyl ester hydrochloride; Z-Dbu-OMe hydrochloride (S-form)
EINECS	Contact for details

Quality Control

Our Z-Dbu-Ome.Hcl (S) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and cGMP applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (S-enantiomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.