Description

Methyl 5-Phosphonopentanoate is a high-purity organophosphorus compound, specifically a phosphonate ester, that serves as a critical building block in advanced organic synthesis. Its value lies in its bifunctional structure, featuring both a phosphonate group and a methyl ester, which makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of bisphosphonate drugs and other bioactive molecules targeting bone metabolism and other therapeutic areas.
• Agrochemical Synthesis: Used to create novel herbicides, plant growth regulators, and fungicides with enhanced efficacy and environmental profiles.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized phosphonate-based ligands used in catalysis and metal coordination chemistry.
• Material Science: Employed in the production of flame retardants, corrosion inhibitors, and surface-modifying agents for polymers and coatings.
• Chemical Biology Probes: Utilized to develop activity-based probes and inhibitors for studying enzyme mechanisms, particularly those involving phosphate transfer.
• Peptidomimetic Research: Acts as a non-hydrolyzable phosphotyrosine mimetic or a linker in the design of peptide analogs and protein-protein interaction inhibitors.

Basic Information

Product Name	Methyl 5-Phosphonopentanoate
CAS No.	1263034-13-4
Molecular Formula	C6H13O5P
Molecular Weight	196.14 g/mol
Synonyms	5-(Methoxycarbonyl)pentylphosphonic Acid; Methyl 5-Phosphonovalerate; 5-Phosphonopentanoic Acid Methyl Ester; Pentanoic Acid, 5-Phosphono-, Methyl Ester; (5-Methoxy-5-oxopentyl)phosphonic Acid; Dimethyl 5-Phosphonopentanoate (common misnomer); Phosphonic Acid, P-(5-Methoxy-5-oxopentyl)-; Methyl Ester of 5-Phosphonopentanoic Acid
EINECS	Contact for details

Quality Control

Our Methyl 5-Phosphonopentanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets exacting specifications for research and commercial use. Certificates of Analysis (COA) detailing all test results are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.