Description

(R)-6-Chloro-2-Methyl-1,2,3,4-Tetrahydroquinoline is a high-purity chiral intermediate of significant importance in advanced organic synthesis. This compound is valued for its role as a key building block in the development of active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating enantiomerically pure products.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Agrochemical Synthesis: Used in the development of enantiomerically pure pesticides and herbicides, where specific stereochemistry is crucial for bioactivity.
• Catalyst Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in asymmetric catalysis.
• Fine Chemical Production: Employed in the manufacture of complex, high-value specialty chemicals requiring precise stereochemical control.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	(R)-6-Chloro-2-Methyl-1,2,3,4-Tetrahydroquinoline
CAS No.	1263000-44-7
Molecular Formula	C10H12ClN
Molecular Weight	181.66 g/mol
Synonyms	(R)-6-Chloro-2-methyl-1,2,3,4-tetrahydroquinoline; (6R)-6-Chloro-2-methyl-1,2,3,4-tetrahydroquinoline; (R)-2-Methyl-6-chloro-1,2,3,4-tetrahydroquinoline; 6-Chloro-2-methyl-1,2,3,4-tetrahydroquinoline, (R)-; Tetrahydroquinoline, 6-chloro-2-methyl-, (R)-; (R)-6-Chloro-2-methyl-3,4-dihydro-1H-quinoline; (R)-6-Chloro-2-methyl-1,2,3,4-tetrahydro-quinoline
EINECS	Contact for details

Quality Control

Our (R)-6-Chloro-2-Methyl-1,2,3,4-Tetrahydroquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.