Description

2-[n-(D-Phenylglycine)]Crotonic Acid Ethyl Ester Potassium Salt is a specialized chiral building block and intermediate of significant interest in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking high-purity intermediates for asymmetric synthesis and process development.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and production of novel APIs, including potential antibiotics and enzyme inhibitors.
• Asymmetric Synthesis: Serves as a building block in stereoselective reactions to introduce the D-phenylglycine moiety into target molecules.
• Peptidomimetic Research: Used in the design and synthesis of peptide analogs and mimetics for drug discovery programs.
• Agrochemical Development: Intermediate in the synthesis of advanced, chiral active ingredients for crop protection.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and process chemistry laboratories.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	2-[n-(D-Phenylglycine)]Crotonic Acid Ethyl Ester Potassium Salt
CAS No.	1262750-76-4
Molecular Formula	C14H16KNO4
Molecular Weight	301.38 g/mol
Synonyms	Potassium (2E)-3-[(2R)-2-amino-2-phenylacetamido]but-2-enoate; Ethyl (2E)-3-[(2R)-2-amino-2-phenylacetamido]but-2-enoate potassium salt; D-Phenylglycine crotonic acid ethyl ester potassium derivative; 2-[(D-Phenylglycyl)amino]crotonic acid ethyl ester potassium salt; (E)-Ethyl 3-((R)-2-amino-2-phenylacetamido)but-2-enoate potassium salt
EINECS	Contact for details

Quality Control

Our 2-[n-(D-Phenylglycine)]Crotonic Acid Ethyl Ester Potassium Salt is manufactured under controlled conditions to ensure high chemical purity and chiral integrity, suitable for demanding synthetic applications. Quality is assured through rigorous analytical testing, including chiral HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profile is provided with each batch to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	Conforms
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.