Description

2-Methyl-5-(Trifluoromethoxy)Cinnamic Acid, 97% is a high-purity fluorinated cinnamic acid derivative, serving as a critical building block in advanced organic synthesis. This compound matters for its unique trifluoromethoxy substituent, which imparts enhanced metabolic stability, lipophilicity, and bioavailability to target molecules. It is primarily needed by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients, as well as by fine chemical manufacturers producing specialty intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the trifluoromethoxy group can improve biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor for fluorinated liquid crystal compounds used in high-performance displays.
• Organic Electronic Materials: Employed in the synthesis of novel organic semiconductors and charge-transport materials.
• Chemical Research & Development: A versatile building block for academic and industrial research exploring new fluorinated organic molecules and reaction pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke intermediates under cGMP or research-grade conditions.

Basic Information

Product Name	2-Methyl-5-(Trifluoromethoxy)Cinnamic Acid, 97%
CAS No.	1262019-25-9
Molecular Formula	C11H9F3O3
Molecular Weight	246.18 g/mol
Synonyms	(E)-3-[2-Methyl-5-(trifluoromethoxy)phenyl]acrylic acid; 3-(2-Methyl-5-(trifluoromethoxy)phenyl)-2-propenoic acid; 2-Methyl-5-(trifluoromethoxy)cinnamic acid; α-Methyl-3-(trifluoromethoxy)cinnamic acid; 5-(Trifluoromethoxy)-2-methylcinnamic acid; (E)-3-(2-Methyl-5-(trifluoromethoxyphenyl)prop-2-enoic acid; Trifluoromethoxy methyl cinnamate acid
EINECS	Contact for details

Quality Control

Our 2-Methyl-5-(Trifluoromethoxy)Cinnamic Acid, 97% is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the specified 97% minimum purity. Certificates of Analysis (COA) with detailed chromatographic data are available upon request for quality assurance and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be stored away from direct light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.