Description

3-Fluoro-3',5'-Dimethoxy-[1,1'-Biphenyl]-4-Carboxylic Acid is a high-purity, functionalized biphenyl derivative serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in the precise combination of fluorine and methoxy substituents, which are essential for modulating the electronic and steric properties of target molecules. This compound is primarily needed by R&D and production teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators, where the biphenyl core provides structural rigidity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or luminescent compounds, due to its conjugated system.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs producing bespoke organic compounds for client projects.
• Academic Research: Used in university and institutional labs for methodological studies in cross-coupling reactions and fluorine chemistry.

Basic Information

Product Name	3-Fluoro-3',5'-Dimethoxy-[1,1'-Biphenyl]-4-Carboxylic Acid
CAS No.	1261980-91-9
Molecular Formula	C15H13FO4
Molecular Weight	276.26 g/mol
Synonyms	[1,1'-Biphenyl]-4-carboxylic acid, 3-fluoro-3',5'-dimethoxy-; 3-Fluoro-3',5'-dimethoxybiphenyl-4-carboxylic acid; 4'-Carboxy-2-fluoro-4,6'-dimethoxybiphenyl; 3-Fluoro-3',5'-dimethoxy-4-biphenylcarboxylic acid; 2-Fluoro-4,6'-dimethoxy-[1,1'-biphenyl]-4'-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-3',5'-Dimethoxy-[1,1'-Biphenyl]-4-Carboxylic Acid is manufactured under a strict quality management system. Our products undergo rigorous quality testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.