Description

5-(4-Chloro-2-Methoxyphenyl)Nicotinic Acid CAS NO 1261980-32-8 is a high-purity, synthetically derived fine chemical building block characterized by its unique substituted phenylnicotinic acid structure. This compound is of significant commercial interest as a key intermediate in the research and development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel drug candidates, particularly in therapeutic areas requiring complex heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated aromatic system.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic processes and material science applications.
• Organic Electronic Materials Research: Investigated as a potential component in the development of organic semiconductors and light-emitting materials due to its conjugated system.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific molecular fragment.

Basic Information

Product Name	5-(4-Chloro-2-Methoxyphenyl)Nicotinic Acid
CAS No.	1261980-32-8
Molecular Formula	C13H10ClNO3
Molecular Weight	263.67 g/mol
Synonyms	5-(4-Chloro-2-methoxyphenyl)pyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 5-(4-chloro-2-methoxyphenyl)-; Nicotinic acid, 5-(4-chloro-2-methoxyphenyl)-; 5-(4-Chloro-2-methoxyphenyl)nicotinate; 1261980-32-8
EINECS	Contact for details

Quality Control

Our 5-(4-Chloro-2-Methoxyphenyl)Nicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 98.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.