Description

4-(3-Cyanophenyl)-2-Fluorophenol is a high-purity fluorinated phenol derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its unique bifunctional structure, combining a cyano-substituted phenyl ring with a fluorophenol moiety, enabling precise molecular construction. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in kinase inhibitor and CNS-active compound research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging the fluorine atom for enhanced bioactivity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for advanced electronic materials, where its rigid, polar structure contributes to desired electro-optical properties.
• Polymer Chemistry: Functional monomer for creating specialty polymers with enhanced thermal stability, chemical resistance, or specific surface properties.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Cross-Coupling Reactions: Valuable substrate in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) for constructing complex biaryl systems.

Basic Information

Product Name	4-(3-Cyanophenyl)-2-Fluorophenol
CAS No.	1261978-55-5
Molecular Formula	C13H8FNO
Molecular Weight	213.21 g/mol
Synonyms	2-Fluoro-4'-(3-cyanophenyl)phenol; 4-(3-Cyanophenyl)-2-fluorophenol; 3-(2-Fluoro-4-hydroxyphenyl)benzonitrile; [1,1'-Biphenyl]-3-carbonitrile, 2'-fluoro-4'-hydroxy-; 2'-Fluoro-4'-hydroxy[1,1'-biphenyl]-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 4-(3-Cyanophenyl)-2-Fluorophenol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Custom purity grades and analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after initial use to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.