Description

3-Fluoro-3'-Nitro-[1,1'-Biphenyl]-4-Carboxylic Acid is a high-purity, multi-functional biphenyl derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate, enabling the construction of complex molecular architectures with precise fluorine and nitro group substitution. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Used in the development of new herbicides and fungicides, where the fluorine atom and biphenyl core can enhance biological activity and environmental stability.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and material science.
• Functional Material Development: Employed in the research of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology Probes: Utilized to build molecular probes for studying enzyme function and biological pathways due to its modifiable carboxylic acid group.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	3-Fluoro-3'-Nitro-[1,1'-Biphenyl]-4-Carboxylic Acid
CAS No.	1261968-85-7
Molecular Formula	C13H8FNO4
Molecular Weight	261.21 g/mol
Synonyms	[1,1'-Biphenyl]-4-carboxylic acid, 3-fluoro-3'-nitro-; 3-Fluoro-3'-nitrobiphenyl-4-carboxylic acid; 4'-Nitro-3-fluoro[1,1'-biphenyl]-4-carboxylic acid; 3-Fluoro-3'-nitro-4-biphenylcarboxylic acid; 3'-Nitro-3-fluoro-4-biphenylcarboxylic acid; 4-Carboxy-3'-fluoro-3-nitrobiphenyl
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-3'-Nitro-[1,1'-Biphenyl]-4-Carboxylic Acid is produced and tested under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.