Description

4-(3-Chloro-4-Methylphenyl)-3-Fluorobenzoic Acid is a high-purity, multi-functional aromatic carboxylic acid derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both chloro and fluoro substituents on distinct aromatic rings, makes it a valuable intermediate for creating compounds with tailored electronic and steric properties. This product is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical sectors, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a core component for synthesizing advanced organic electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Polymer Modifier: Incorporated as a monomer or additive to impart specific properties like thermal stability, flame retardancy, or unique solubility to high-performance polymers.
• Chemical Research: A versatile reagent in academic and industrial R&D for exploring new coupling reactions, catalysis, and material science applications.
• Custom Synthesis: The foundational structure for contract manufacturing organizations (CMOs) to produce bespoke fine chemicals and complex molecules for client-specific projects.

Basic Information

Product Name	4-(3-Chloro-4-Methylphenyl)-3-Fluorobenzoic Acid
CAS No.	1261965-53-0
Molecular Formula	C14H10ClFO2
Molecular Weight	264.68 g/mol
Synonyms	3-Fluoro-4'-(3-chloro-4-methylphenyl)benzoic Acid; 3-Fluoro-4-(3-chloro-4-methylphenyl)benzoic Acid; 4-(3-Chloro-p-tolyl)-3-fluorobenzoic Acid; Benzoic acid, 4-(3-chloro-4-methylphenyl)-3-fluoro-; 1261965-53-0; AKOS026713065; F2198-6478; 4-(3-chloro-4-methylphenyl)-3-fluorobenzoic acid
EINECS	Contact for details

Quality Control

Every batch of 4-(3-Chloro-4-Methylphenyl)-3-Fluorobenzoic Acid is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and purity. Our standard quality commitment includes comprehensive analysis via HPLC, GC, NMR, and MS to verify identity, potency, and impurity profiles. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.