Description

3-Chloro-3'-Fluoro-[1,1'-Biphenyl]-4,4'-Dicarboxylic Acid is a high-purity biphenyl dicarboxylic acid derivative, serving as a critical advanced intermediate in the synthesis of complex organic molecules. Its value lies in the precise functionalization with chlorine and fluorine substituents, which are essential for tuning the electronic and steric properties of target compounds. This product is primarily needed by R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors for developing active ingredients and functional monomers.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel Active Pharmaceutical Ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the biphenyl core provides structural rigidity and the halogens influence bioactivity.
• Liquid Crystal & OLED Materials: Serves as a precursor for dicarboxylic acid derivatives used in the manufacture of liquid crystal displays (LCDs) and organic light-emitting diode (OLED) materials.
• Polymer & Resin Chemistry: Functions as a monomer or cross-linking agent in the production of high-performance polyesters, polyamides, and epoxy resins with enhanced thermal stability.
• Metal-Organic Framework (MOF) Precursor: Employed as an organic linker in the construction of novel MOFs for gas storage, separation, and catalysis applications.
• Organic Synthesis & Catalysis Research: A versatile substrate in academic and industrial research for developing new coupling reactions and catalytic processes.

Basic Information

Product Name	3-Chloro-3'-Fluoro-[1,1'-Biphenyl]-4,4'-Dicarboxylic Acid
CAS No.	1261964-19-5
Molecular Formula	C14H8ClFO4
Molecular Weight	294.66 g/mol
Synonyms	4,4'-Biphenyldicarboxylic Acid, 3-Chloro-3'-fluoro-; 3'-Fluoro-3-chloro-4,4'-biphenyldicarboxylic Acid; 3-Chloro-3'-fluorobiphenyl-4,4'-dicarboxylic Acid; [1,1'-Biphenyl]-4,4'-dicarboxylic acid, 3-chloro-3'-fluoro-; Biphenyl-4,4'-dicarboxylic acid, 3-chloro-3'-fluoro- derivative
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-3'-Fluoro-[1,1'-Biphenyl]-4,4'-Dicarboxylic Acid is manufactured under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing key parameters such as purity, identity, and impurity profiles to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.