Description

8-Bromo-6-Trifluoromethoxyquinoline, Hcl is a high-purity, halogenated quinoline derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmacophore and versatile building block for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily utilized by research institutions and fine chemical manufacturers engaged in medicinal chemistry, material science, and the synthesis of complex heterocyclic molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive quinoline core.
• Material Science: Serves as a building block for creating advanced organic electronic materials and ligands for catalysis.
• Medicinal Chemistry R&D: Employed in structure-activity relationship (SAR) studies and library synthesis for high-throughput screening.
• Fine Chemical Synthesis: Utilized for the preparation of complex, multi-functionalized quinoline derivatives for specialized applications.

Basic Information

Product Name	8-Bromo-6-Trifluoromethoxyquinoline, Hcl
CAS No.	1261956-53-9
Molecular Formula	C₁₁H₆BrF₃NO•HCl
Molecular Weight	342.53 g/mol (Free base: 306.07 g/mol)
Synonyms	8-Bromo-6-(trifluoromethoxy)quinoline hydrochloride; 6-Trifluoromethoxy-8-bromoquinoline HCl; Quinoline, 8-bromo-6-(trifluoromethoxy)-, hydrochloride; 8-Bromo-6-trifluoromethoxyquinoline hydrochloride salt
EINECS	Contact for details

Quality Control

Our 8-Bromo-6-Trifluoromethoxyquinoline, Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and traceability for your research and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.