Description

4-Fluoro-3-(4-Methylphenyl)Benzoic Acid is a high-value fluorinated aromatic carboxylic acid derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a fluorine atom and a biaryl motif, makes it an essential intermediate for creating compounds with tailored electronic and steric properties. This product is primarily targeted at research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, where the fluorine atom can enhance bioavailability and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs), due to its rigid, conjugated structure.
• Polymer Chemistry: Can be incorporated as a monomer or additive to impart specific properties like thermal stability or hydrophobicity to high-performance polymers.
• Chemical Research: Employed in academic and industrial R&D for studying structure-activity relationships (SAR) and developing new synthetic methodologies involving fluorinated aromatics.
• Coordination Chemistry: Acts as a ligand precursor for metal-organic frameworks (MOFs) and catalysts, leveraging the carboxylic acid group for metal binding.

Basic Information

Product Name	4-Fluoro-3-(4-Methylphenyl)Benzoic Acid
CAS No.	1261953-27-8
Molecular Formula	C14H11FO2
Molecular Weight	230.24 g/mol
Synonyms	3-(4-Methylphenyl)-4-fluorobenzoic acid; 4'-Methyl-4-fluoro-[1,1'-biphenyl]-3-carboxylic acid; 4-Fluoro-3-(p-tolyl)benzoic acid; [1,1'-Biphenyl]-3-carboxylic acid, 4-fluoro-4'-methyl-; 4-Fluoro-3-(4'-methylphenyl)benzoic acid; 4-Fluoro-3-(4-methylphenyl)benzoic acid CAS 1261953-27-8
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-(4-Methylphenyl)Benzoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.