Description

5-(4-Fluoro-3-Methoxyphenyl)Nicotinic Acid CAS NO 1261934-09-1 is a high-purity, functionalized nicotinic acid derivative, serving as a critical pharmaceutical intermediate and organic building block for advanced chemical synthesis. Its unique molecular structure, featuring both fluoro and methoxy substituents on the phenyl ring, makes it invaluable for constructing complex molecules with tailored biological activity and physicochemical properties. This compound is primarily sought by pharmaceutical R&D and fine chemical manufacturers engaged in developing new active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Agrochemical Synthesis: Building block for developing advanced herbicides and fungicides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions in fine chemical production.
• Material Science Research: Intermediate for synthesizing functional organic molecules used in organic light-emitting diodes (OLEDs) and other electronic materials.
• Chemical Biology Probes: Serves as a core structure for creating molecular probes to study enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	5-(4-Fluoro-3-Methoxyphenyl)Nicotinic Acid
CAS No.	1261934-09-1
Molecular Formula	C13H10FNO3
Molecular Weight	247.22 g/mol
Synonyms	5-(4-Fluoro-3-methoxyphenyl)pyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 5-(4-fluoro-3-methoxyphenyl)-; Nicotinic acid, 5-(4-fluoro-3-methoxyphenyl)-; 5-(4-Fluoro-3-methoxyphenyl)-3-pyridinecarboxylic acid; 5-(4-Fluoro-3-methoxyphenyl)nicotinate; FMPNA (abbreviation)
EINECS	Contact for details

Quality Control

Our production of 5-(4-Fluoro-3-Methoxyphenyl)Nicotinic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and MS. We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing all specified parameters to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.