Description

5-Chloro-3-(Thiophen-3-Yl)Benzoic Acid is a high-value, multi-functional aromatic carboxylic acid derivative that serves as a critical synthetic intermediate. Its molecular architecture, featuring both a benzoic acid core and a thiophene heterocycle, makes it an essential building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and advanced material synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiophene moiety.
• Material Science: Serves as a monomer or functionalizing agent in the production of specialty polymers, liquid crystals, and organic semiconductors for electronic applications.
• Chemical Synthesis: Acts as a versatile building block for Suzuki-Miyaura and other cross-coupling reactions to create complex biaryl systems for further chemical exploration.
• Academic & Contract Research: Employed in university and CRO laboratories for method development, library synthesis, and investigating structure-activity relationships (SAR).

Basic Information

Product Name	5-Chloro-3-(Thiophen-3-Yl)Benzoic Acid
CAS No.	1261926-16-2
Molecular Formula	C11H7ClO2S
Molecular Weight	238.69 g/mol
Synonyms	3-(3-Thienyl)-5-chlorobenzoic Acid; 5-Chloro-3-(3-thienyl)benzoic Acid; Benzoic acid, 5-chloro-3-(3-thienyl)-; 5-Chloro-3-thiophen-3-yl-benzoic acid; 1261926-16-2; AKOS026710293; 5-chloro-3-(thiophen-3-yl)benzoic acid
EINECS	Contact for details

Quality Control

Every batch of 5-Chloro-3-(Thiophen-3-Yl)Benzoic Acid is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard research-grade material typically meets a purity specification of ≥95% (HPLC). Certificates of Analysis (COA) detailing batch-specific results from techniques such as HPLC, NMR, and LC-MS are provided and available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.