Description

3-(4-Boc-Aminophenyl)Phenol is a high-purity, protected aniline derivative that serves as a critical building block in advanced organic synthesis. Its value lies in the orthogonal protection of the amine group, which allows for selective chemical transformations in complex multi-step sequences. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, especially those containing biphenyl or aniline motifs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides.
• Peptide Mimetics & Linker Chemistry: Employed in the construction of peptide-like structures and as a component in cleavable linkers for prodrugs or bioconjugates.
• Material Science Research: Acts as a monomer or functionalization agent in the development of specialty polymers and advanced organic materials.
• Chemical Biology Probes: Useful for creating tagged molecules to study biological pathways and interactions.

Basic Information

Product Name	3-(4-Boc-Aminophenyl)Phenol
CAS No.	1261916-66-8
Molecular Formula	C17H19NO3
Molecular Weight	285.34 g/mol
Synonyms	4-(3-Hydroxyphenyl)aniline, tert-butyl carbamate; tert-Butyl N-[4-(3-hydroxyphenyl)phenyl]carbamate; 3-(4-((tert-Butoxycarbonyl)amino)phenyl)phenol; 4'-Amino-[1,1'-biphenyl]-3-ol, N-Boc protected; BOC-4-Aminobiphenyl-3-ol; N-Boc-4'-amino-3-hydroxybiphenyl
EINECS	Contact for details

Quality Control

Our 3-(4-Boc-Aminophenyl)Phenol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC, NMR, and mass spectrometry, to verify identity and purity. A Certificate of Analysis (COA) is supplied with each batch, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider holding the material under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.