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5-Fluoro-3-(4-Methoxyphenyl)Benzoic Acid CAS NO 1261903-69-8
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CAS No.:1261903-69-8
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
5-Fluoro-3-(4-Methoxyphenyl)Benzoic Acid is a high-purity fluorinated aromatic carboxylic acid derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both fluorine and methoxy substituents, makes it a valuable intermediate for creating compounds with tailored electronic and steric properties. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and functional materials.
Application
- Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
- Agrochemical Research: Used in developing novel herbicides, fungicides, and plant growth regulators, where the fluorine atom enhances biological activity and metabolic stability.
- Liquid Crystal & OLED Materials: Serves as a core component for synthesizing advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
- Polymer Modification: Acts as a monomer or functionalizing agent to introduce fluorine and aromatic groups into polymer chains, improving thermal stability and chemical resistance.
- Chemical Synthesis Reagent: Employed in Suzuki-Miyaura and other cross-coupling reactions to construct complex biaryl systems prevalent in modern medicinal chemistry.
- Academic & Contract Research: A vital tool for academic institutions and CROs (Contract Research Organizations) conducting research in synthetic methodology and material science.
Basic Information
| Product Name | 5-Fluoro-3-(4-Methoxyphenyl)Benzoic Acid |
| CAS No. | 1261903-69-8 |
| Molecular Formula | C14H11FO3 |
| Molecular Weight | 246.24 g/mol |
| Synonyms | 3-(4-Methoxyphenyl)-5-fluorobenzoic Acid; 5-Fluoro-3-(4-methoxyphenyl)benzoic Acid; Benzoic acid, 5-fluoro-3-(4-methoxyphenyl)-; [1,1'-Biphenyl]-3-carboxylic acid, 4'-methoxy-5-fluoro-; 4'-Methoxy-5-fluoro[1,1'-biphenyl]-3-carboxylic acid |
| EINECS | Contact for details |
Quality Control
Our 5-Fluoro-3-(4-Methoxyphenyl)Benzoic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications. For custom synthesis projects, we adhere to cGMP guidelines where required to support regulatory filings.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Conforms to reference |
| Assay (HPLC) | ≥98.0% |
| Related Substances (HPLC) | Total impurities ≤2.0% |
| Loss on Drying | ≤0.5% |
| Residue on Ignition | ≤0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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