Description

4'-Methoxy-5-(Trifluoromethyl)-[1,1'-Biphenyl]-3-Carboxylic Acid is a high-value biphenyl carboxylic acid derivative distinguished by its methoxy and trifluoromethyl substituents. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry. It is primarily required by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of small molecule drugs, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides and fungicides, leveraging the stability imparted by the trifluoromethyl group.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials and liquid crystals due to its rigid biphenyl core.
• Custom Synthesis & Contract Manufacturing: A pivotal starting material for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Product Name	4'-Methoxy-5-(Trifluoromethyl)-[1,1'-Biphenyl]-3-Carboxylic Acid
CAS No.	1261902-93-5
Molecular Formula	C15H11F3O3
Molecular Weight	296.24 g/mol
Synonyms	5-(Trifluoromethyl)-4'-methoxybiphenyl-3-carboxylic acid; [1,1'-Biphenyl]-3-carboxylic acid, 4'-methoxy-5-(trifluoromethyl)-; 4'-Methoxy-5-(trifluoromethyl)biphenyl-3-carboxylic acid; 3-Biphenylcarboxylic acid, 4'-methoxy-5-(trifluoromethyl)-; 4'-Methoxy-5-trifluoromethyl-[1,1'-biphenyl]-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 4'-Methoxy-5-(Trifluoromethyl)-[1,1'-Biphenyl]-3-Carboxylic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are available for every shipment. We support development and commercial projects with material suitable for research use through to cGMP-grade manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.