Description

Methyl 4-Fluoro-4'-Hydroxybiphenyl-3-Carboxylate is a high-purity biphenyl derivative that serves as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its bifunctional molecular structure, featuring both a fluorinated aromatic ring and a phenolic hydroxyl group, which makes it a versatile building block for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and advanced materials sectors who require precise, reliable intermediates for developing active pharmaceutical ingredients (APIs) and specialty polymers.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Liquid Crystal Materials: Used in the research and production of fluorinated liquid crystals for advanced display technologies.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for electron-transport or host materials in OLED device fabrication.
• Agrochemical Synthesis: Employed in the development of new-generation herbicides and fungicides with enhanced activity.
• Polymer Chemistry: Acts as a monomer or chain modifier for engineering plastics and high-performance polymers.
• Chemical Research: Utilized in academic and industrial R&D for studying structure-activity relationships and developing new synthetic methodologies.

Basic Information

Product Name	Methyl 4-Fluoro-4'-Hydroxybiphenyl-3-Carboxylate
CAS No.	1261900-28-0
Molecular Formula	C14H11FO3
Molecular Weight	246.24 g/mol
Synonyms	Methyl 3-(4-Fluoro-4'-hydroxybiphenyl)carboxylate; 4'-Hydroxy-4-fluoro[1,1'-biphenyl]-3-carboxylic Acid Methyl Ester; 3-Carbomethoxy-4'-hydroxy-4-fluorobiphenyl; MFHBP; 4-Fluoro-4'-hydroxybiphenyl-3-carboxylic Acid Methyl Ester; Biphenyl-3-carboxylic acid, 4-fluoro-4'-hydroxy-, methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 4-Fluoro-4'-Hydroxybiphenyl-3-Carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR to verify identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) documenting full specifications are provided with every shipment. We support cGMP-compliant manufacturing for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture absorption. Store away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.