Description

3-Chloro-5-(4-Fluorophenyl)Phenol CAS NO 1261897-12-4 is a high-purity halogenated phenolic compound, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its unique molecular structure, which combines phenolic, chloro, and fluorophenyl functionalities, enabling precise chemical modifications. This product is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it is used to build complex active molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging the bioactivity of the halogenated phenol core.
• Material Science Precursor: Serves as a monomer or functionalization agent in the production of specialty polymers and high-performance resins.
• Liquid Crystal & OLED Materials: Acts as an intermediate in the synthesis of fluorinated components for electronic display and lighting technologies.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a scaffold for further functional group transformations in R&D laboratories.

Basic Information

Product Name	3-Chloro-5-(4-Fluorophenyl)Phenol
CAS No.	1261897-12-4
Molecular Formula	C12H8ClFO
Molecular Weight	222.64 g/mol
Synonyms	3-Chloro-5-(4-fluorophenyl)phenol; 5-(4-Fluorophenyl)-3-chlorophenol; 1-Chloro-3-hydroxy-5-(4-fluorophenyl)benzene; (4-Fluorophenyl)-5-chloro-3-phenol; 1261897-12-4; 3-Chloro-5-(p-fluorophenyl)phenol; Phenol, 3-chloro-5-(4-fluorophenyl)-
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-(4-Fluorophenyl)Phenol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) with lot-specific data are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.