Description

2-(4-Trifluoromethoxyphenyl)Phenol is a high-purity fluorinated phenolic compound serving as a critical advanced intermediate in organic synthesis. Its unique structure, featuring both a phenol and a trifluoromethoxy group, makes it a valuable building block for creating complex molecules with enhanced properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the trifluoromethoxy group can improve biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated components for liquid crystal displays (LCDs), contributing to improved dielectric anisotropy and thermal stability.
• Polymer Modification: Acts as a monomer or additive for synthesizing specialty polymers, such as polyarylates and epoxy resins, to enhance flame retardancy and chemical resistance.
• Organic Electronics: Investigated as a core structure in the development of organic semiconductors and charge-transport materials for OLEDs and photovoltaic cells.
• Chemical Research: A versatile reagent for academic and industrial research in cross-coupling reactions, such as Suzuki and Buchwald-Hartwig aminations, to create novel biaryl structures.

Basic Information

Product Name	2-(4-Trifluoromethoxyphenyl)Phenol
CAS No.	1261896-51-8
Molecular Formula	C13H9F3O2
Molecular Weight	254.21 g/mol
Synonyms	2-(4-(Trifluoromethoxy)phenyl)phenol; [1,1'-Biphenyl]-2-ol, 4'-(trifluoromethoxy)-; 4'-(Trifluoromethoxy)[1,1'-biphenyl]-2-ol; 2-Hydroxy-4'-(trifluoromethoxy)biphenyl; 2-Phenylphenol, 4'-trifluoromethoxy derivative; o-Phenylphenol, 4'-trifluoromethoxy-; (2-Hydroxyphenyl)(4-(trifluoromethoxy)phenyl)methane
EINECS	Contact for details

Quality Control

Our 2-(4-Trifluoromethoxyphenyl)Phenol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) documenting all critical parameters are available upon request, and we support custom purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. The compound is light-sensitive; prolonged exposure to light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.