Description

3-Chloro-3'-Fluoro-4'-Methyl-[1,1'-Biphenyl]-4-Carboxylic Acid CAS NO 1261893-13-3 is a high-purity, multi-substituted biphenyl carboxylic acid derivative. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile organic synthesis building block for constructing complex molecular architectures. It is essential for research and development teams in the pharmaceutical, agrochemical, and material science industries seeking to develop new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and plant growth regulators, leveraging the biphenyl core for bioactivity.
• Liquid Crystal & OLED Materials: Serves as a precursor for the synthesis of specialized organic electronic materials, where the substituted biphenyl structure contributes to desired mesogenic or emissive properties.
• Organic Ligand Precursor: Utilized in metallorganic chemistry and catalysis research to create complex ligands for transition metal catalysts.
• Polymer Modification: Acts as a monomer or functionalization agent for engineering polymers with specific thermal, optical, or mechanical characteristics.
• Chemical Research & Development: A valuable tool for medicinal chemists and synthetic organic chemists exploring structure-activity relationships (SAR) and novel chemical spaces.

Basic Information

Item	Detail
Product Name	3-Chloro-3'-Fluoro-4'-Methyl-[1,1'-Biphenyl]-4-Carboxylic Acid
CAS No.	1261893-13-3
Molecular Formula	C14H10ClFO2
Molecular Weight	264.68 g/mol
Synonyms	3-Chloro-3'-fluoro-4'-methylbiphenyl-4-carboxylic acid; 4'-Methyl-3-chloro-3'-fluorobiphenyl-4-carboxylic acid; [1,1'-Biphenyl]-4-carboxylic acid, 3-chloro-3'-fluoro-4'-methyl-; Biphenyl-4-carboxylic acid, 3-chloro-3'-fluoro-4'-methyl-
EINECS	Contact for details

Quality Control

Our production of 3-Chloro-3'-Fluoro-4'-Methyl-[1,1'-Biphenyl]-4-Carboxylic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and organic solvents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.