Description

4-(4-Carboxyphenyl)-2-Chlorobenzoic Acid is a high-purity, bifunctional aromatic carboxylic acid derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in providing a versatile, halogenated biphenyl scaffold for constructing complex molecules with precise spatial and electronic properties. This compound is essential for research chemists and process development teams in the pharmaceutical, agrochemical, and specialty materials industries seeking to develop new active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in developing kinase inhibitors, anti-inflammatory agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators, leveraging its halogenated biphenyl core.
• Liquid Crystal & OLED Materials: Serves as a precursor for synthesizing specialized monomers and ligands used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modification: Acts as a functional monomer or cross-linking agent to introduce carboxylic acid groups and chlorinated aromatic units into polymers, enhancing thermal stability and adhesion properties.
• Metal-Organic Framework (MOF) Precursor: Utilized as an organic linker in the construction of porous coordination polymers and MOFs for catalysis, gas storage, and separation applications.
• Chemical Research & Development: A versatile starting material in academic and industrial R&D for exploring new organic reactions and creating complex molecular architectures.

Basic Information

Product Name	4-(4-Carboxyphenyl)-2-Chlorobenzoic Acid
CAS No.	1261891-38-6
Molecular Formula	C14H9ClO4
Molecular Weight	276.67 g/mol
Synonyms	2-Chloro-4'-(carboxy)[1,1'-biphenyl]-4-carboxylic Acid; 2'-Chloro-[1,1'-biphenyl]-4,4'-dicarboxylic Acid; 4-(2-Chloro-4-carboxyphenyl)benzoic Acid; 4-Carboxyphenyl-2-chlorobenzoic Acid; Biphenyl-4,4'-dicarboxylic Acid, 2'-Chloro- Derivative; 2-Chlorobiphenyl-4,4'-dicarboxylic Acid
EINECS	Contact for details

Quality Control

Our production of 4-(4-Carboxyphenyl)-2-Chlorobenzoic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent absorption of atmospheric moisture, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.