Description

3-Hydroxy-6-(Trifluoromethoxy)Quinoline is a high-value, multi-functional heterocyclic building block distinguished by its trifluoromethoxy and hydroxyl substituents. This compound is critical for researchers and manufacturers requiring precise molecular scaffolds to impart desirable properties like metabolic stability and enhanced lipophilicity in advanced materials. It is primarily utilized in the pharmaceutical and agrochemical sectors for the research and development of novel active ingredients, as well as in materials science for creating specialized functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in developing new-generation pesticides and herbicides, where the trifluoromethoxy group can enhance biological activity and environmental stability.
• Ligand & Catalyst Development: Acts as a versatile ligand or a core structure in metal-organic frameworks (MOFs) and catalytic systems.
• Organic Electronic Materials: Investigated as a building block for electron-transport materials, OLEDs, and other advanced organic semiconductors.
• Fluorescent Probe Synthesis: Utilized in creating sensitive chemical sensors and bio-imaging agents due to the inherent fluorescence of the quinoline core.
• Chemical Research & Development: A valuable reagent for method development and exploring novel organic reactions in academic and industrial R&D laboratories.

Basic Information

Product Name	3-Hydroxy-6-(Trifluoromethoxy)Quinoline
CAS No.	1261868-42-1
Molecular Formula	C₁₀H₆F₃NO₂
Molecular Weight	229.16 g/mol
Synonyms	6-(Trifluoromethoxy)quinolin-3-ol; 3-Hydroxy-6-(trifluoromethoxy)quinoline; Quinolin-3-ol, 6-(trifluoromethoxy)-; 6-Trifluoromethoxyquinolin-3-ol; 3-Quinolinol, 6-(trifluoromethoxy)-
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-6-(Trifluoromethoxy)Quinoline is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality system supports development from laboratory to commercial scale, ensuring reliable supply for critical R&D and production applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.