Description

2-(4-Iodo-2-Nitrophenyl)Acetic Acid is a specialized aromatic building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, featuring both an iodo and a nitro substituent on the phenyl ring, which makes it a versatile intermediate for constructing complex molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as medicinal chemistry, ligand synthesis, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting specific receptor sites.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or plant growth regulators, leveraging its halogenated nitroaromatic structure.
• Ligand and Catalyst Synthesis: Employed in the preparation of specialized ligands for transition metal catalysis or as a building block for functional materials.
• Chemical Biology Probes: Acts as a starting material for synthesizing molecular probes and tags used in biochemical and cellular imaging studies.
• Advanced Organic Synthesis: Utilized in cross-coupling reactions (e.g., Suzuki, Sonogashira) where the iodine atom serves as an excellent leaving group, enabling further functionalization.
• Dye and Pigment Intermediate: Potential use in the synthesis of complex colorants and functional dyes due to its nitroaromatic core.

Basic Information

Product Name	2-(4-Iodo-2-Nitrophenyl)Acetic Acid
CAS No.	1261853-80-8
Molecular Formula	C8H6INO4
Molecular Weight	307.05 g/mol
Synonyms	(4-Iodo-2-nitrophenyl)acetic acid; 2-(4-Iodo-2-nitrophenyl)ethanoic acid; 4-Iodo-2-nitrophenylacetic acid; Acetic acid, 2-(4-iodo-2-nitrophenyl)-; 1261853-80-8; 2-(4-Iodo-2-nitro-phenyl)-acetic acid
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. For this high-purity synthetic intermediate, quality is assured through multiple analytical techniques. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing parameters such as purity (HPLC), identity (IR, NMR), and impurity profiles. Our quality management system supports custom synthesis projects with strict adherence to client specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.