Description

2-(Difluoromethoxy)Quinolin-6-Ol is a specialized quinoline derivative characterized by a difluoromethoxy substituent, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in enabling the precise introduction of fluorinated motifs, which are essential for modulating the physicochemical and biological properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in developing novel pesticides and herbicides where the difluoromethoxy group enhances metabolic stability and bioavailability.
• Material Science Precursor: Serves as a monomer or functionalizing agent for creating specialty polymers and organic electronic materials.
• Fluorination Chemistry Studies: A valuable reference compound in academic and industrial research exploring new fluorination methodologies and reaction mechanisms.
• Ligand Synthesis: Utilized for constructing complex chelating ligands used in catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2-(Difluoromethoxy)Quinolin-6-Ol
CAS No.	1261745-73-6
Molecular Formula	C₁₀H₇F₂NO₂
Molecular Weight	211.17 g/mol
Synonyms	6-Hydroxy-2-(difluoromethoxy)quinoline; 2-(Difluoromethoxy)-6-hydroxyquinoline; Quinolin-6-ol, 2-(difluoromethoxy)-; 1261745-73-6
EINECS	Contact for details

Quality Control

Our 2-(Difluoromethoxy)Quinolin-6-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced intermediate use. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.