Description

4-[(2-Trifluoromethyl)Phenyl]-Pyridine-2-Carboxylic Acid CAS NO 1261745-31-6 is a high-purity, advanced pharmaceutical intermediate featuring a unique trifluoromethylphenyl-pyridine scaffold. This compound is a critical building block in modern medicinal chemistry, valued for its ability to modulate the pharmacokinetic and binding properties of target molecules. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring high specificity.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, especially kinase inhibitors and receptor antagonists.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides with enhanced efficacy and environmental profiles.
• Material Science: Serves as a precursor for functionalized ligands and monomers in the creation of specialty polymers and advanced materials.
• Chemical Synthesis: Employed as a versatile building block for constructing complex heterocyclic compounds in organic and medicinal chemistry.
• Life Science Research: Utilized in biochemical tool development for probing biological pathways and protein functions.

Basic Information

Product Name	4-[(2-Trifluoromethyl)Phenyl]-Pyridine-2-Carboxylic Acid
CAS No.	1261745-31-6
Molecular Formula	C13H8F3NO2
Molecular Weight	267.21 g/mol
Synonyms	2-Pyridinecarboxylic acid, 4-[2-(trifluoromethyl)phenyl]-; 4-(2-(Trifluoromethyl)phenyl)picolinic acid; 4-(α,α,α-Trifluoro-o-tolyl)picolinic acid; 4-(2-Trifluoromethylphenyl)-2-pyridinecarboxylic acid; 1261745-31-6; 4-(2-Trifluoromethylphenyl)picolinic acid
EINECS	Contact for details

Quality Control

Our 4-[(2-Trifluoromethyl)Phenyl]-Pyridine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.