Description

2-Chloro-4-(Trifluoromethoxy)Benzoic Acid is a high-value, multi-functional aromatic carboxylic acid derivative, distinguished by its unique trifluoromethoxy and chloro substituents. This compound serves as a critical advanced intermediate in modern synthetic chemistry, enabling the development of novel molecules with enhanced properties. It is primarily sought after by R&D and production teams in the pharmaceutical and agrochemical industries for synthesizing active ingredients and complex organic frameworks.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group contributes to improved biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of specialty chemicals for electronic displays, leveraging its aromatic core and halogenated structure.
• Polymer & Resin Modifiers: Acts as a monomer or additive to introduce specific functional groups into polymer chains, enhancing material properties like thermal stability or chemical resistance.
• Organic Synthesis & Catalysis: A versatile reagent in cross-coupling reactions, esterification, and amide bond formation for constructing complex molecular architectures in academic and industrial research.
• Chemical Research & Development: Essential reference standard and starting material in method development and exploratory chemistry within fine chemical and contract research organizations.

Basic Information

Product Name	2-Chloro-4-(Trifluoromethoxy)Benzoic Acid
CAS No.	1261731-19-4
Molecular Formula	C8H4ClF3O3
Molecular Weight	240.56 g/mol
Synonyms	2-Chloro-4-(trifluoromethoxy)benzoic acid; Benzoic acid, 2-chloro-4-(trifluoromethoxy)-; 4-(Trifluoromethoxy)-2-chlorobenzoic acid; 2-Chloro-α,α,α-trifluoro-p-anisic acid; 2-Chloro-4-trifluoromethoxybenzoic acid; 2-Chloro-4-(trifluoromethoxy)benzenecarboxylic acid; 1261731-19-4
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-4-(Trifluoromethoxy)Benzoic Acid is manufactured and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy to ensure identity, purity, and consistency meet the exacting standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.