Description

3-Fluoroquinolin-5-Ol is a high-purity fluorinated quinoline derivative, a key building block in advanced organic synthesis. Its value lies in its unique molecular structure, which serves as a versatile scaffold for developing novel active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to innovate with fluorinated heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated drug candidates, particularly in oncology, anti-infective, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used to develop new generations of herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and environmental stability.
• Material Science: Serves as a building block for creating advanced organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport layers.
• Chemical Synthesis: Acts as a versatile fluorinated synthon for constructing complex heterocyclic systems in medicinal and process chemistry.
• Ligand & Catalyst Development: Utilized in the design of novel ligands for catalysis and metal-organic frameworks (MOFs) due to its chelating potential.

Basic Information

Product Name	3-Fluoroquinolin-5-Ol
CAS No.	1261729-67-2
Molecular Formula	C9H6FNO
Molecular Weight	163.15 g/mol
Synonyms	5-Hydroxy-3-fluoroquinoline; 3-Fluoro-5-hydroxyquinoline; 3-Fluoro-5-quinolinol; 3-Fluoroquinolin-5-ol; Quinolin-5-ol, 3-fluoro-; 1261729-67-2
EINECS	Contact for details

Quality Control

Our 3-Fluoroquinolin-5-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed specifications for trace impurities, residual solvents, and heavy metals, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere when not in use to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.