Description

3-(2-Fluoro-4-Hydroxyphenyl)Propanoic Acid is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound is valued for its unique molecular structure, which incorporates both a phenolic hydroxyl group and a fluorine atom on the phenyl ring, enabling precise modifications in target molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for creating fluorinated analogs with enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators where the fluorine moiety improves efficacy and environmental profile.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated aromatic cores in electronic display and lighting materials.
• Bioconjugation & Probe Development: Utilized in biochemical research for attaching fluorophores or other functional groups to biomolecules via its carboxylic acid group.
• Polymer Modification: Acts as a monomer or modifier to introduce fluorine and phenolic functionality into specialty polymers, enhancing their thermal and chemical resistance.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, including cross-coupling and fluorination reactions.

Basic Information

Product Name	3-(2-Fluoro-4-Hydroxyphenyl)Propanoic Acid
CAS No.	1261674-98-9
Molecular Formula	C9H9FO3
Molecular Weight	184.16 g/mol
Synonyms	2-Fluoro-4-(2-carboxyethyl)phenol; 3-(2-Fluoro-4-hydroxyphenyl)propionic Acid; Benzenepropanoic acid, 2-fluoro-4-hydroxy-; 4-Hydroxy-2-fluorobenzenepropanoic Acid; 2-Fluoro-4-hydroxyhydrocinnamic Acid; FL-4-HPPA; F-4-HPPA
EINECS	Contact for details

Quality Control

Our production of 3-(2-Fluoro-4-Hydroxyphenyl)Propanoic Acid adheres to stringent quality management protocols. Each batch is analyzed using advanced techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality system is designed to support cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents, strong bases, and acid chlorides.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.