Description

3-Methoxy-4-(Trifluoromethoxy)Benzoic Acid is a high-value, multi-functional aromatic carboxylic acid derivative, distinguished by its methoxy and trifluoromethoxy substituents. This compound is a critical synthetic intermediate prized for its ability to impart unique physicochemical properties, such as enhanced lipophilicity and metabolic stability, into target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group can improve bioactivity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for mesogens and electron-transport materials in display technologies and organic light-emitting diodes (OLEDs).
• Polymer Modification: Employed to introduce functional benzoic acid groups into polymer chains, altering thermal and chemical resistance properties.
• Organic Synthesis & Catalysis: Acts as a versatile reagent in coupling reactions (e.g., Suzuki, Heck) and as a ligand precursor in catalytic systems.
• Chemical Research & Development: Utilized in academic and industrial R&D for exploring new chemical entities and structure-activity relationships (SAR).

Basic Information

Product Name	3-Methoxy-4-(Trifluoromethoxy)Benzoic Acid
CAS No.	1261652-99-6
Molecular Formula	C9H7F3O4
Molecular Weight	236.15 g/mol
Synonyms	3-Methoxy-4-(trifluoromethoxy)benzoic acid; 4-(Trifluoromethoxy)-3-methoxybenzoic acid; Benzoic acid, 3-methoxy-4-(trifluoromethoxy)-; 3-Methoxy-4-trifluoromethoxybenzoic acid; 1261652-99-6; 3-Methoxy-α,α,α-trifluoro-p-anisic acid; 4-Carboxy-2-methoxy-1-(trifluoromethoxy)benzene
EINECS	Contact for details

Quality Control

Every batch of 3-Methoxy-4-(Trifluoromethoxy)Benzoic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the precise requirements of your application. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for each lot and supplied upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.